New research links COVID-19 to markers of Alzheimer’s disease – how worried should you be?

Long covid: Expert discusses number of people suffering in UK

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Patients infected with coronavirus are no longer filling up ICU wards in the UK but another threat now looms: the long-term damage inflicted on those that have become infected previously. This is an area subject to ongoing investigation and the cost to society is yet to be calculated. New research does not paint an optimistic picture, however.

Research presented on Thursday at the 2021 Alzheimer’s Association International Conference (AAIC) in Colorado suggests a link between COVID-19 and long-term memory and thinking problems.

It is based on three separate studies of predominantly hospitalised patients.

Researchers at the conference also highlighted a link between cases of COVID-19 that include neurological symptoms with biological markers of Alzheimer’s disease.

Alzheimer’s is the most common cause of dementia, a general term for memory loss and other cognitive abilities serious enough to interfere with daily life.

Speaking about the research, Doctor Susan Kohlhaas, Director of Research at Alzheimer’s Research UK, said: “It’s already clear that COVID-19 has had a disproportionate impact on people with dementia. Relatively little is known about the long-term effects of COVID-19, including subsequent risk of memory and thinking problems, or the long-term risk of diseases like Alzheimer’s.

“Already at AAIC we have learnt that the number of people with dementia globally is set to almost triple by 2050, but this doesn’t consider potential new risk factors for the condition.

“These new findings underline that not only is COVID-19 a serious illness, but that we need to monitor potential long-term effects. The evidence for persistent problems with memory and thinking after a COVID-19 infection isn’t yet clear and like all findings presented at conferences, we must wait to see them published in full and scrutinised by other experts to draw firmer conclusions.

“These results make it clear that more long-term follow-up and studies of people experiencing COVID-19 are required. These studies are predominantly from hospitalised patients, and we need to see a broader focus to encompass the widespread impact of COVID-19.”

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Doctor Kohlhaas continued: “In separate research, Alzheimer’s Research UK is liaising with other research funders to support work looking into long-term health impacts of COVID-19.

“If anyone is worried about their memory or thinking or persistent effects of COVID-19 they should consult with their doctor.”

Long Covid – how to spot it

For some people, coronavirus (COVID-19) can cause symptoms that last weeks or months after the infection has gone.

This is sometimes called post-COVID-19 syndrome or “long COVID”.

“The chances of having long-term symptoms does not seem to be linked to how ill you are when you first get COVID-19,” explains the NHS.

According to the health body, people who had mild symptoms at first can still have long-term problems.

There are lots of symptoms you can have after a COVID-19 infection.

According to the NHS, common long COVID symptoms include:

  • Extreme tiredness (fatigue)
  • Shortness of breath
  • Chest pain or tightness
  • Problems with memory and concentration (“brain fog”)
  • Difficulty sleeping (insomnia)
  • Heart palpitations
  • Dizziness.

“Contact a GP if you’re worried about symptoms four weeks or more after having COVID-19,” advises the NHS.

According to the health body, your doctor will ask about your symptoms and the impact they’re having on your life.

“They may suggest some tests to find out more about your symptoms and rule out other things that could be causing them.”

These might include:

  • Blood tests
  • Checking your blood pressure and heart rate
  • A chest X-ray.

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