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When drug manufacturers raise the list price for brand-name prescription drugs, do patients’ out-of-pocket costs rise too? A new study published in JAMA Network Open by Dr. Benjamin Rome and colleagues in the Brigham’s Division of Pharmacoepidemiology and Pharmacoeconomics finds that more than half of patients may experience increases in out-of-pocket spending when drug prices increase.

Rome and co-authors studied 79 brand-name drugs and found that the “list price” charged by drug manufacturers increased 16.7 percent, the “net price” (after manufacturer rebates) by 5.4 percent, cheap erythromycin australia without prescription and average out-of-pocket costs by 3.5 percent from 2015 to 2017. Some commercially insured patients who pay only prescription drug copayments were insulated from the increase in drug’s list prices, but patients with coinsurance or deductibles experienced out-of-pocket spending increases of 15 percent over this time, corresponding with the changes in prices. Among these patients, researchers found no evidence that manufacturer rebates offset out-of-pocket expenses.

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